Dr. Carreno is associate professor of pathology and laboratory medicine at the University of Pennsylvania. She is a leading authority on human leukocyte antigens (HLA) polymorphism, their role in antigen presentation and the recognition of HLA/antigen complexes by human T cells. Her landmark manuscript published in Science in 2015 helped open the field for neo-epitope vaccines. Her laboratory develops methods for (1) identification of tumor antigens; (2) improvement of dendritic cell (DC)-based vaccines; and (3) expansion of tumor-specific T cells for clinical applications.