Renowned for his investigations of cancer pathogenesis, Dr. Croce has provided valuable insights into the underlying, genetic basis of cancer onset. His research has established genetic links to a variety of cancers including Burkitt ‘s lymphoma, T-Cell lymphoma, and acute leukemia. His discoveries have shown that chromosomal abnormalities such as translocations are capable of contributing to both cancer initiation and progression.
In addition to his studies involving genes such as ALL1 and TCL1, Dr. Croce was the first investigator to discover and sequence BCL2. He later defined a role for this protein in various lymphomas such as follicular lymphoma. More recently, Dr. Croce ‘s work has centered on understanding the role of micro RNAs in cancer pathogenesis. His research has proved that particular micro RNAs have the potential to exhibit either oncogenic or tumor suppressive properties. While heavily involved in research, Dr. Croce also served as editor-in-chief for Cancer Research (1990-1999).
Career Highlights
2017 AACR Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research
2011 Szent-Györgyi Prize for Progress in Cancer Research
2011 Elected Member, Institute of Medicine
2010 Elected Fellow, American Academy of Arts and Sciences
2006 AACR-G.H.A. Clowes Memorial Award
2005 Jeffrey A. Gottlieb Memorial Award, UT MD Anderson Cancer Center
2004 John W. Wolfe Chair in Human Cancer Genetics, The Ohio State University
2003 President of the Republic Prize, Accademia di Lincei
2003 Italian Gold Medal for Public Health
2000 Honor of Merit of Italian Republic
1999 AACR-Pezcoller International Award for Cancer Research
1999 Raymond Bourgine Award and Gold Medal of Paris
1996 Elected Member, National Academy of Sciences, Washington, DC
1993 Charles S. Mott Prize, General Motors Cancer Research Foundation
1990 AACR-Richard and Hinda Rosenthal Foundation Award
1969 MD, University of Rome