An Exosome-based Liquid Biopsy Shows Promise for Early Detection of Pancreatic Cancer
SAN DIEGO – An investigational exosome-based liquid biopsy accurately detected 97% of stage 1-2 pancreatic cancers when combined with...
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Next-generation PARP Inhibitor Demonstrates Clinical Benefit in Patients with Homologous Recombination Repair-deficient Breast Cancer
Drug has higher selectivity for PARP1, improving safety and tolerability SAN DIEGO – Saruparib, a selective inhibitor of poly-ADP...
Adagrasib Plus Cetuximab May Provide Clinical Benefit in Patients With KRASG12C-mutated Colorectal Cancer
SAN DIEGO – A combination of the KRASG12C inhibitor adagrasib (Krazati) and the anti-epidermal growth factor receptor (EGFR) antibody...
A Biologic Drug-Device Combination Immunotherapy Shows Promise for Patients with Metastatic Prostate Cancer
The investigational therapy uses a cold-temperature probe to kill a portion of prostate cancer cells and release tumor-specific neoantigens...
Fewer Than Half of Accelerated Approval Drugs Showed Clinical Benefit in Confirmatory Trials After Five Years
SAN DIEGO – Of the 46 cancer drugs that the U.S. Food and Drug Administration (FDA) granted accelerated approval...
Accelerated Aging May Increase the Risk of Early-onset Cancers in Younger Generations
SAN DIEGO – Accelerated aging was more common in recent birth cohorts and was associated with increased incidence of...
Immune Response to Investigational RNA Vaccine for Pancreatic Cancer Continues to Correlate with Clinical Benefit
Results are from a median follow-up of three years SAN DIEGO – An adjuvant treatment regimen that included autogene...
Bispecific Immune Checkpoint Inhibitor Improves Survival in Gastric Cancer Patients Regardless of PD-L1 Status
SAN DIEGO – The PD-1/CTLA-4 bispecific antibody cadonilimab plus chemotherapy improved progression-free survival and overall survival in patients with...
AACR Recognizes 2023-2024 Research Grantees
PHILADELPHIA — The American Association for Cancer Research (AACR) today announced its newest class of grant recipients. Since 1993, the AACR...
Pfizer Chairman and CEO Dr. Albert Bourla to Receive the 2024 AACR Outstanding Achievement Award for Service to Cancer Science and Medicine
The American Association for Cancer Research (AACR) will honor Pfizer Inc., as well as Pfizer’s chairman and chief executive...