Cancer Preventive Vaccine Showed Promising Results in Preclinical Model of Lynch Syndrome
“ATLANTA – Vaccination with as few as four tumor antigens generated antigen-specific responses, reduced intestinal tumors, and improved survival...
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Gilteritinib Improved Survival for Patients With Acute Myeloid Leukemia
“ATLANTA – Treatment with the FLT3-targeted therapeutic gilteritinib (Xospata) improved survival for patients with relapsed or refractory acute myeloid...
Emil J Freireich Honored With AACR Award for Lifetime Achievement in Cancer Research
PHILADELPHIA – The American Association for Cancer Research (AACR) recognized Emil J Freireich, MD, FAACR, with the 2019 AACR...
Excess Body Weight Before age 50 is Associated With Higher Risk of Dying From Pancreatic Cancer
ATLANTA – Excess weight before age 50 may be more strongly associated with pancreatic cancer mortality risk than excess...
Mesothelin-targeted CAR T-cell Therapy Safe, Shows Early Promise in Patients With Advanced Solid Tumors
ATLANTA – A chimeric antigen receptor (CAR) T-cell therapy that targets the protein mesothelin showed no evidence of major...
HER2-targeted CAR T-cell Therapy Safe, With Promising Antitumor Activity in Patients With Advanced Sarcoma
ATLANTA – A combination of chemotherapy and chimeric antigen receptor (CAR) T cells designed to target the protein HER2...
Immune Checkpoint Inhibitor Combination Efficacious For Patients With High-grade Neuroendocrine Carcinoma
ATLANTA – A combination of the anti-CTLA-4 immunotherapeutic ipilimumab (Yervoy) and the anti-PD-1 immunotherapeutic nivolumab (Opdivo) showed clinical benefit...
Adding the MET Inhibitor Savolitinib to Osimertinib was Beneficial for Certain Pretreated Lung Cancer Patients in TATTON Trial
ATLANTA – Adding the investigational MET inhibitor savolitinib to the EGFR inhibitor osimertinib (Tagrisso) yielded clinical responses in patients...
Dr. Cornelis J.M. Melief Honored With 2019 AACR-CRI Lloyd J. Old Award in Cancer Immunology
PHILADELPHIA – The American Association for Cancer Research (AACR) will recognize Cornelis J.M. Melief, MD, PhD, with the seventh...
Antoni Ribas, MD, PhD, Elected American Association for Cancer Research President-Elect 2019-2020
Five new members elected to the Board of Directors PHILADELPHIA – The members of the American Association for Cancer...