Immunotherapy research has exploded over the past decade and has led to the approval of seven immune checkpoint inhibitors by the United States Food and Drug Administration (FDA) for the treatment...
In the early 1990s, Gregg Semenza, MD, PhD, was a postdoctoral researcher studying the cellular response to reduced oxygen levels, a...
The days are getting longer and warmer, and visions of beach trips, cookouts, and picnics occupy our minds. While this year’s summer will likely look different due to the ongoing COVID-19 pandemic, months...
Signaling pathways that regulate cellular proliferation are commonly mutated in cancer cells, leading to unrestrained cellular division and tumor growth. Therefore, insight into the...
The unrestrained cellular proliferation that characterizes cancer largely arises due to genetic mutations, which can impede the regulatory mechanisms that control when and how often a cell divides. Genetic mutations may also...
Bladder cancer is a common malignancy originating in the bladder, a hollow organ located in the abdomen that stores urine. It is the sixth most prevalent cancer in the United...
Over the past decade, immune checkpoint inhibitors have transformed cancer care for a variety of tumor types. This form of immunotherapy can lead to long-lasting...
While the incidence of melanoma has been rising, the mortality rate has experienced a steep decline over the past few years. This is largely attributable...
Testicular cancer forms when cancerous cells develop in one or both testicles. Almost all cases of the disease begin...
Multiple myeloma is a cancer of antibody-producing cells—called plasma cells—that accounts for approximately 1.8 percent of new cancer cases...