AACR-Novocure Career Development Award for Tumor Treating Fields Research in Ovarian Cancer
The AACR-Novocure Career Development Award for Tumor Treating Fields Research in Ovarian Cancer represents a joint effort to promote and support early-career investigators to conduct innovative research focused on Tumor Treating Fields (TTFields; intermediate frequency, low intensity, alternating electric fields that disrupt cell division in cancer cells) in ovarian cancer. This grant is intended to provide a deeper understanding of the mechanisms of action of this novel anti-cancer treatment modality and to accelerate the development of new treatment strategies to advance therapeutic options for ovarian cancer. Research projects should examine the use of TTFields as a therapeutic modality in ovarian cancer.
This grant provides $300,000 over three years for expenses related to the research project, which may include salary and benefits of the grant recipient and any collaborators*, postdoctoral or clinical research fellows, graduate students (including tuition costs associated with graduate students’ education and training), or research assistants; research/laboratory supplies; equipment; publication charges for manuscripts that pertain directly to the funded project; and other research expenses; and indirect costs. (*Note that inter-laboratory collaboration is encouraged.)
Download Program Guidelines and Application Instructions here.
Research proposals must incorporate use of the Inovitro® system into the experimental design. For grant recipients who are affiliated with institutions that do not currently hold a Materials Transfer Agreement (MTA) with Novocure for use of its devices, Novocure will provide this system to complete the research. For additional details, please see the MTA and Terms and Conditions. If selected for funding, Novocure will work with the institution to execute an MTA.
Research projects should examine the use of TTFields as a therapeutic modality in ovarian cancer. Proposals may include 1) Basic and translational approaches, promoting the transition of TTFields in vitro work into in vivo systems, 2) Studies that link preclinical and clinical data, or 3) Studies with ability to translate into the clinic for the treatment of ovarian cancer.
Projects focused on one or more of the areas outlined below are strongly encouraged:
- Key cancer-related signaling and cellular pathways
- Metabolic effects of TTFields
- Studies that include Omics data (genomics, transcriptomic, proteomics)
- TTFields immunological aspects in ovarian cancer and the potential combination with immunotherapy
- Combinational studies with approved agents, preferably to include mechanistic aspects
Institutions may submit multiple applications for the AACR-Novocure Career Development Award for Tumor Treating Fields Research in Ovarian Cancer and the AACR-Novocure Tumor Treating Fields Research in NSCLC Grants for multiple applicants. However, no more than one applicant will be awarded from the same department of an institution.
Applicants must have a doctoral degree (PhD, MD, MD/PhD, or equivalent) in a related field and not currently be a candidate for a further doctoral degree.
At the start of the grant term on December 1, 2022, applicants must:
- Hold a faculty position with the title of assistant professor, instructor, research assistant professor, or the equivalent.
- If eligibility is based on a future position, the position must be confirmed at the time of application and CANNOT be contingent upon receiving this grant.
- If the future position is at a different institution than the applicant’s current institution, the applicant must contact the AACR’s Scientific Review and Grants Administration Department (the AACR’s SRGA) at [email protected] before submitting their application for information on additional verification materials/signatures that may be required.
- Have completed their most recent doctoral degree within the past 11 years (i.e., degree cannot have been conferred before December 1, 2011; the formal date of receipt of doctoral degree is the date the degree was conferred, as indicated on their diploma and/or transcript).
- Applicants with a medical degree must have completed their most recent doctoral degree or medical residency (or equivalent) - whichever date is later - within the past 11 years.
- Have independent laboratory space as confirmed by their institution.
- Work at an academic, medical, or research institution anywhere in the world.
There are no citizenship requirements. However, by submitting an application for this grant, an applicant applying from an institution located in a country in which they are not a citizen or permanent resident assures that the visa status will provide sufficient time to complete the project and grant term at the institution from which they applied.
Applicants must be AACR Active members. Nonmembers interested in this grant opportunity must submit a satisfactory application for AACR Active membership by the application deadline. Nonmembers can apply for membership online. Members can renew their membership through myAACR to bring their membership current. You will need your logon (email address) and password to access the member portal. If you require assistance logging in, please submit a help form. Lapsed members must be members in good standing by the application deadline and should contact the Membership Department at [email protected] for assistance.
The AACR requires applicants to submit an online application by 1:00 p.m. U.S. Eastern Time on Tuesday, September 20, 2022 using the ProposalCentral website at https://proposalcentral.com/.
Download Program Guidelines and Application Instructions here.