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NextGen Stars

AACR Annual Meeting 2023 NextGen Stars Program 

The NextGen Stars program provides an exciting opportunity to increase the visibility of early-career scientists at the AACR Annual Meeting and to support their professional development and advancement.

cONGRATULATIONS TO THE 2023 nEXTgEN sTARS!

Timour Baslan, PhD

Timour Baslan, PhD

Postdoctoral Fellow

Memorial Sloan Kettering Cancer Center, New York, New York

Ordered and selective patterns of cancer genome evolution revealed by lineage tracing of sporadic p53 loss

Major Symposium SY28

New Insights into Cancer Initiation, Progression, and Therapy through Big Data Resources

Sunday, April 16, 2023

Doratha A. Byrd, MPH, PhD

Doratha A. Byrd, MPH, PhD

Assistant Member         

Moffitt Cancer Center, Tampa, Florida

A biobank of Fecal Immunochemical Tests (FIT) for gut microbiome measurement: A paradigm for studying the microbiome and cancer

Major Symposium SY22

Microbiome and Cancer Immunotherapy

Tuesday, April 18, 2023

 

Katelyn T. Byrne, PhD

Katelyn T. Byrne, PhD

Assistant Professor of Cell, Developmental and Cancer Biology

Oregon Health and Science University, Portland, Oregon

Agonistic anti-CD40 converts regulatory T cells in to Type 1 effector cells within the tumor microenvironment

Major Symposium SY12

T Cells and the Tumor

Monday, April 17, 2023

Michael Chiorazzi, MD, PhD

Michael Chiorazzi, MD, PhD

Assistant Professor of Internal Medicine (Medical Oncology)

Yale School of Medicine, New Haven, Connecticut

Autologous humanized PDX modeling for immuno-oncology recapitulates the human tumor microenvironment

 Major Symposium SY09

Cancer Ecosystem and the Microenvironment

Wednesday, April 19, 2023

Courtney L. Jones, PhD

Courtney L. Jones, PhD

Scientist, Princess Margaret Cancer Centre; Assistant Professor, University of Toronto

Toronto, Ontario, Canada

Targeting polyamine metabolism in acute myeloid leukemia stem cells

Major Symposium SY03

Stress, Stemness, and Drug Resistance

Tuesday, April 18, 2023

Brittany D. Lord, PhD, MPH

Brittany D. Lord, PhD, MPH

Cancer Prevention Fellow, Division of Cancer Prevention

National Cancer Institute, Bethesda, Maryland

The impact of neighborhood deprivation on DNA methylation in breast cancer from a diverse cohort

Advances in Organ Site Research AOS08

Advances in Breast Cancer

Tuesday, April 18, 2023

Alvin P. Makohon-Moore, PhD

Alvin P. Makohon-Moore, PhD

Assistant Member

Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Hampshire

Transcriptional and metabolic dynamics of cancer cells under nutrient deprivation

Major Symposium SY07

Metabolic Influence on the Cancer Cell State

Tuesday, April 18, 2023 

Rachel N. Martini, PhD

Rachel N. Martini, PhD

Postdoctoral Research Associate

Weill Cornell Medical College, New York, New York

Multiomics in disparities research: Identifying African ancestry-specific mechanisms in the triple negative breast cancer tumor microenvironment

Advances in the Science of Cancer Disparities ASD01

The Biology Driving Cancer Disparities

Monday, April 17, 2023 

Chemtai Mungo, MD, MPH

Chemtai Mungo, MD, MPH

Assistant Professor, Obstetrics and Gynecology

University of North Carolina, Chapel Hill, North Carolina

Feasibility of topical self-administered therapies to improve cervical precancer treatment outcomes among women living with HIV in low-and middle-income countries

Major Symposium SY36

Global Cancer Burden: Challenges and Opportunities for Innovation

Wednesday, April 19, 2023

Jason R. Pitarresi, PhD

Jason R. Pitarresi, PhD

Assistant Professor

University of Massachusetts Chan Medical School, Worcester, Massachusetts

Altered calcium signaling in cancer: PTHrP-KRAS collateral amplification governs pancreatic cancer metastasis, cachexia, and immunosuppression

Major Symposium SY20

Systemic Effects of Cancer

Wednesday, April 19, 2023

Alvaro Quintanal-Villalonga, PhD

Alvaro Quintanal-Villalonga, PhD

Assistant Attending Biologist and Codirector, Rudin Lab

Memorial Sloan Kettering Cancer Center, New York, New York

Multi-omic approaches to study the role of plasticity in therapy resistance and metastasis in lung cancer

Advances in Diagnostics and Therapeutics ADT06

Multiomics in Diagnosis and Care Management

Monday, April 17, 2023 

Megan K. Ruhland, PhD

Megan K. Ruhland, PhD

Assistant Professor of Cell, Developmental and Cancer Biology, and Dermatology

Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon

Dendritic cell intrinsic androgen receptor signaling reduces dendritic cell function and anti-tumor immunity

Major Symposium SY15

Clinical Strategies for Myeloid Cell Modulation in Cancer

Sunday, April 16, 2023 

Anastasia N. Tikhonova, PhD

Anastasia N. Tikhonova, PhD

Scientist, Princess Margaret Cancer Centre; Assistant Professor, University of Toronto

Toronto, Ontario, Canada

Delineating the developmental hierarchy and immune microenvironment of T-cell acute lymphoblastic leukemia

Advances in Organ Site Research AOS05

Advances in Leukemia Research and Treatment

Monday, April 17, 2023

Duo Xu, PhD

Duo Xu, PhD

Research Associate

Weill Cornell Medicine, New York, New York

Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets

Advances in Organ Site Research AOS06

Advances in Prostate Cancer

Wednesday, April 19, 2023

View the abstracts of the NextGen Stars’ presentations from the AACR Annual Meeting 2022:

Mustapha Abubakar, MD, PhD

Mustapha Abubakar, MD, PhD

Research Fellow, Division of Cancer Epidemiology and Genetics

National Cancer Institute, Rockville, Maryland

Double-edged “soil”: Stromal microenvironment in breast cancer

Major Symposium SY25

Metabolic and Nutritional Regulation of Cancer and Immunity

Tuesday, April 12, 2022

Ana Luisa Correia, PhD

Ana Luisa Correia, PhD

Principal Investigator, Cancer Dormancy and Immunity Lab

Champalimaud Foundation, Lisbon, Portugal

Revisiting NK cell immunity to prevent metastasis

Major Symposium SY31

Tumor Dormancy

Sunday, April 10, 2022

Isra Elhussin, MBBS, MSc, PhD candidate

Isra Elhussin, MBBS, MSc, PhD candidate

Tuskegee University, Tuskegee, Alabama

Prostate cancer: Multi-omics comparison between European, African American, and Native African men with prostate cancer

 

Advances in Organ Site Research AOS08

The Next Generation of Targets for Prostate Cancer

Monday, April 11, 2022

Ekrem Emrah Er, PhD

Ekrem Emrah Er, PhD

Assistant Professor, Department of Physiology and Biophysics

University of Illinois at Chicago, Chicago, Illinois

Elevated cellular stiffness sensitizes metastatic cells to destruction by mechanosurveillance: The mechanical mode of immune surveillance

Major Symposium SY23

Extracellular Matrix Remodeling in Cancer

Tuesday, April 12, 2022

Ariella Hanker, PhD

Ariella Hanker, PhD

Assistant Professor, Simmons Comprehensive Cancer Center

The University of Texas Southwestern Medical Center, Dallas, Texas

It takes two: Cooperating oncogenic mutations in the HER2/HER3 pathway

 

Advances in Organ Site Research AOS02

Triple Negative Breast Cancer: Molecular Insights and Treatment Advances

Monday, April 11, 2022

Daniel Herranz, PharmD, PhD

Daniel Herranz, PharmD, PhD

Assistant Professor of Pharmacology

Rutgers Cancer Institute, New Brunswick, New Jersey

Identification of SIRT1 as a novel therapeutic target in T-ALL

 Major Symposium SY04

Epigenetic Alterations as Cancer Therapeutic Targets

Monday, April 11, 2022

Sarah J. Hill, MD, PhD

Sarah J. Hill, MD, PhD

Assistant Professor, Medical Oncology/Molecular and Cellular Oncology

Dana-Farber Cancer Institute, Boston, Massachusetts

Dissecting mechanisms of NK cell dysfunction and re-engagement in high grade serous ovarian cancer

 Advances in Organ Site Research AOS10

Advances in Ovarian Cancer Screening and Treatment

Monday, April 11, 2022

William L. Hwang, MD, PhD

William L. Hwang, MD, PhD

Radiation Oncologist and Research Fellow

Massachusetts General Hospital Cancer Center/Harvard Medical School, Boston, Massachusetts

Multicellular spatial community featuring a novel neuronal-like malignant phenotype is enriched in pancreatic cancer after neoadjuvant chemotherapy and radiotherapy

 Major Symposium SY12

 Nerves, Cancer, and Immunity

 Monday, April 11, 2022

Anand G. Patel, MD, PhD

Anand G. Patel, MD, PhD

Instructor, Department of Oncology

St. Jude Children’s Research Hospital, Memphis, Tennessee

The myogenesis program drives clonal selection and drug resistance in pediatric rhabdomyosarcoma

Advances in Organ Site Research AOS09

Models for Rare Cancers

Tuesday, April 12, 2022

Arja Ray, PhD

Arja Ray, PhD

Postdoctoral Fellow, Department of Pathology

University of California San Francisco, San Francisco, California

Next-generation macrophage and T cell activation reporters to define functional immune states in solid tumors

 Major Symposium SY19

Myeloid Cell Control of Therapeutic Antitumor Immunity

Tuesday, April 12, 2022

Marcus Ruscetti, PhD

Marcus Ruscetti, PhD

Assistant Professor, Department of Molecular Cell and Cancer Biology

University of Massachusetts Chan Medical School, Worcester, Massachusetts

 Modulating cellular senescence to reinstate natural killer cell immunity for pancreatic cancer immunotherapy

 Major Symposium SY24

Aging and the Tumor Microenvironment’s Impact on Minimal Residual Disease    and Cancer Recurrence

Wednesday, April 13, 2022

Ayesha Shafi, PhD

Ayesha Shafi, PhD

Assistant Professor, Center for Prostate Disease Research

Uniformed Services University of the Health Sciences/The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland

The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair

 Presidential Select Symposium SY33

Aging, Stress, and Cancer

 Monday, April 11, 2022

Katherine Tossas, PhD, MS

Katherine Tossas, PhD, MS

Assistant Professor, Department of Health Behavior & Policy

Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia

The vaginal microbiome may operate differently by race to precipitate the risk of pre-cervical cancer

 Advances in Population Sciences APS01

Where You Live Matters: From Biological to Social Determinants of Cancer Outcomes

Tuesday, April 12, 2022

Derek Wainwright, PhD

Derek Wainwright, PhD

Assistant Professor, Departments of Neurological Surgery, Medicine, and Immunology

Northwestern University Feinberg School of Medicine, Chicago, Illinois

IDO: Going beyond enzyme activity to eradicate glioblastoma

 Advances in Organ Site Research AOS13

Advances in Glioblastoma Cancer Research and Cancer Care

Monday, April 11, 2022