Program: Tuesday, February 25
tuesday, february 25
- Major Symposia 4-5
- Neoadjuvant Immunotherapy
- Myeloid Cell Checkpoints
- Major Symposia 6-7
- Engineered T Cells for Solid Tumors
- Inflammation and Cancer
- Keynote Session 3
- Spotlight Sessions 3-4
- Tertiary Lymphoid Structures in Cancer
- CAR-T in Vivo Delivery
CONTINENTAL BREAKFAST
7-8 a.m.
Major Symposia 4-5
8-9:30 a.m.
Major Symposium 4: Neoadjuvant Immunotherapy
Session Chair: Christian Blank, Netherlands Cancer Institute, Amsterdam, Netherlands
- 8:05 a.m. | Neoadjuvant immunotherapy in lung cancer: preclinical models, clinical trials and reverse translation
Tina Cascone, The University of Texas MD Anderson Cancer Center, Houston, Texas - 8:25 a.m. | Neoadjuvant immunotherapy: What can we learn from melanoma to optimize patient outcomes
Georgina V. Long, University of Sydney, Sydney, NSW, Australia - 8:45 a.m. | Full personalization of neoadjuvant therapy: The next steps
Christian Blank - 9:05 a.m. | Discussion / Q&A
Major Symposium 5: Myeloid Cell Checkpoints
Session Chair: Miriam Merad, Icahn School of Medicine at Mount Sinai, New York, New York
- 8:05 a.m. | Leveraging single technologies to engineer the immune system
Ido Amit, Weizmann Institute of Science, Rehovot, Israel - 8:25 a.m. | Spatio-temporal regulation of tumor associated macrophages
Florent Ginhoux, Gustave Roussy, Villejuif, France - 8:45 a.m.
Miriam Merad - 9:05 a.m. | Discussion / Q&A
BREAK
9:30-9:50 a.m.
Major SymposiA 6-7
10-11:30 a.m.
Major Symposium 6: engineered T Cells for Solid Tumors
Session Chair: Philip D. Greenberg, Fred Hutchinson Cancer Center, Seattle, Washington
- 10:05 a.m.
Kole Roybal, University of California, San Francisco, California - 10:25 a.m.
Christine E. Brown, City of Hope National Medical Center, Duarte, California - 10:45 a.m.
Philip D. Greenberg - 11:05 a.m. | Discussion / Q&A
Major Symposium 7: Inflammation and Cancer
Session Chair: Robert Vonderheide, Penn Medicine Abramson Cancer Center, Philadelphia, Pennsylvania
- 10:05 a.m.
Michael Karin, University of California, San Diego, California - 10:25 a.m. | KRAS inhibitors and modulation of inflammation and immunity
Robert H. Vonderheide - 10:45 a.m. | Theraparticles for inside-out neutrophil control in acute inflammation
Lola Eniola Adefeso, University of Illinois Chicago, Chicago, Illinois - 11:05 a.m. | Discussion / Q&A
BREAK
11:30 a.m.-12 p.m.
keynote session 3
12-1 p.m.
Session Chair: Philip D. Greenberg, Fred Hutchinson Cancer Center, Seattle, Washington
- 12:05 p.m.
Crystal L. Mackall, Stanford University School of Medicine, Stanford, California - 12:35 p.m.
Carl H. June, University of Pennsylvania, Philadelphia, Pennsylvania
Spotlight on Proffered Papers Session 2
1-1:45 p.m.
Poster Session B / Exhibit Show / Lunch
1:45-4:45 p.m.
spotlight SESSIONS 3 AND 4
5-6:20 p.m.
Spotlight Session 3: Tertiary Lymphoid Structures in Cancer
Session Chair: Daniela Thommen, Netherlands Cancer Institute, Amsterdam, Netherlands
- 5:05 p.m. | Cell interactions that modulate PD-1+ CD8 T cell responses
Alice O. Kamphorst, Icahn School of Medicine at Mount Sinai, New York, New York - 5:25 p.m. | Impact of tertiary lymphoid structures on the tumor-specific T cell landscape
Daniela Thommen - 5:45 p.m. | Antibody responses in intra-tumoral Tertiary Lymphoid Structures antagonize the progression of human cancer
Jose R. Conejo-Garcia, Duke Cancer Institute, Durham, North Carolina - 6:05 p.m. | Discussion / Q&A
Spotlight Session 4: CAR-T in vivo Delivery
Session Chair: Michael Birnbaum, Koch Institute for Integrative Cancer Research at MIT, Cambridge, Massachusetts
- 5:05 p.m. | Antigen-specific viral targeting of T cells
Michael Birnbaum - 5:25 p.m. | Direct in vivo transduction of T and NK cells to treat B cell malignancies
Saar Gill, University of Pennsylvania, Philadelphia, Pennsylvania - 5:45 p.m.
Jennifer Hamilton, Azalea Therapeutics, Berkeley, California - 6:05 p.m. | Discussion / Q&A
evening off
6:20 p.m.