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AACR Special Conference in Cancer Research: Mechanisms of Cancer Immunity and Cancer-related Autoimmunity

In association with the Cancer Immunology Working Group

September 24-27, 2025
Doubletree by Hilton Montreal
Montreal, QC, Canada

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Conference Cochairs

Ana C. Anderson, Harvard Medical School and Brigham and Women’s Hospital, Boston, Massachusetts
Sandra Demaria, Weill Cornell Medical College, New York, New York
Kunle Odunsi, University of Chicago Medicine Comprehensive Cancer Center, Chicago, Illinois
E. John Wherry, University of Pennsylvania, Philadelphia, Pennsylvania

Malignant transformations are often associated with autoimmunity induction and the generation of autoantibodies. Conversely, chronic inflammation can promote malignant transformation. Moreover, immunotherapies such as checkpoint blockade can provoke autoimmunity and immunoregulatory therapies used for inflammatory diseases can predispose to malignancy. This AACR Special Conference will focus on the mechanisms responsible for cancer immunity and autoimmunity and the intersection of these two diseases. Special focus will be placed upon the role of genetics, epigenetics, microbiome, immune cell subsets, innate immune pathways, and leveraging therapeutic developments across these diseases.