Program
Friday, February 21, 2020
Saturday, February 22, 2020
- Plenary Session 1: Microbiota Role in Metabolism and Immunity
- Plenary Session 2: Microbiota and Colon Cancer
- Plenary Session 3: Oncogenic Viruses, Part 1
Sunday, February 23, 2020
- Plenary Session 4: Tumor-Associated Microbiota
- Plenary Session 5: Oncogenic Viruses, Part 2
- Plenary Session 6: Microbiota and Gastrointestinal Cancers
- Second Keynote Address
Monday, February 24, 2020
- Plenary Session 7: Microbiota in Cancer Prevention and Therapy, Part 1
- Plenary Session 8: Microbiota in Cancer Prevention and Therapy, Part 2
Friday, February 21
Welcome and Opening Keynote Address
6-7:15 p.m.
Molecular control of the gut microbiome to improve cancer chemotherapy
Matthew Redinbo, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Opening Reception
7:15-9:15 p.m.
Saturday, February 22
Continental Breakfast
7:30-8 a.m.
Plenary Session 1: Microbiota Role in Metabolism and Immunity
Session Chair: Giorgio Trinchieri, National Cancer Institute, Bethesda, Maryland
8:30-10:30 a.m.
Host microbiome interactions in health and disease
Eran Elinav, Weizmann Institute of Science, Rehovot, Israel
Control over colorectal tumor growth via bacteria-specific T cell activation of the local immune response
Timothy W. Hand, University of Pittsburgh R.K. Mellon Institute for Pediatric Research, Pittsburgh, Pennsylvania
Title to be announced
Michael A. Fischbach, Stanford University, Stanford, California
Microbiota, metabolites and anti-tumor immunity
Kathy D. McCoy, University of Calgary, Calgary, Alberta, Canada
Break
10:30-10:45 a.m.
Plenary Session 2: Microbiota and Colon Cancer
Session Chair: Jennifer A. Wargo, The University of Texas MD Anderson cancer Center, Houston, Texas
10:45 a.m.-12:45 p.m.
Colon cancer: Microbes and communities in microbiome translation
Cynthia L. Sears, Johns Hopkins University School of Medicine, Baltimore, Maryland
The plasticity of the intestinal microbiota in colorectal cancer
Christian Jobin, University of Florida, Gainsville, Flordia
Title to be announced
Laurence Zitvogel, Gustave Roussy Cancer Center, Villejuif, France
Right-sided colonic biofilms are associated with adenoma formation in patients with Lynch syndrome*
Carlijn Bruggeling, Radboudumc, Nijmegen, Gelderland, The Netherlands
A mutational signature in human colorectal cancer induced by genotoxic pks+ E. coli*
Jens Puschhof, Hubrecht Institute, Utrecht, Provincie Utrecht, The Netherlands
Poster Session A / Lunch
12:45-2:45 p.m.
Plenary Session 3: Oncogenic Viruses, Part 1
Session Chair: Cynthia L. Sears, Johns Hopkins University School of Medicine, Baltimore, Maryland
3-5 p.m.
The particulars of circulars: Novel RNAs from oncogenic herpesviruses
Yuan Chang, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Epigenetic remodeling of host metabolic pathways by Epstein-Barr Virus (EBV) immortalization
Paul M. Lieberman, The Wistar Institute, Philadelphia, Pennsylvania
Bladder cancers affecting transplant recipients harbor diverse viruses that associate with overall survival
Christopher B. Buck, National Cancer Institute, Bethesda, Maryland
Functional characterization of the enteric animal virome as mediator of host health*
Simone Dallari, New York University School of Medicine, New York, New York
Potential of metformin to modify the gut microbiota and prevent inflammation in nondiabetic people with HIV*
Jean-Pierre Routy, McGill University Health Centre, Montreal, Québec, Canada
Evening Off / Dinner on Own
5 p.m.
Sunday, February 23
Continental Breakfast
7-8 a.m.
Plenary Session 4: Tumor-Associated Microbiota
Session Chair: Laurence Zitvogel, Gustave Roussy Cancer Center, Villejuif, France
8-10 a.m.
Fusobacterium persistence and antibiotic response in colorectal cancer
Susan Bullman, Fred Hutchinson Cancer Research Center, Seattle, Washington
Regulation of pancreatic oncogenesis by pathogens
Deepak Saxena, New York University College of Dentistry, New York, New York
Characterizing the tumor microbiome and its effects on response to therapy
Ravid Straussman, Weizmann Institute of Science, Rehovot, Israel
Elucidating role of bacteria during pancreatic ductal adenocarcinoma (PDAC)*
Vidhi Chandra, The University of Texas MD Anderson Cancer Center, Houston, Texas
Bacteroides fragilis: A potential pathogen orchestrating EMT and stemness in breast epithelial cells via concomitant activation of Notch and βcatenin axes*
Dipali Sharma, Johns Hopkins University, Baltimore, Maryland
Break
10-10:15 a.m.
Plenary Session 5: Oncogenic Viruses, Part 2
Session Chair: Cynthia L. Sears, Johns Hopkins University School of Medicine, Baltimore, Maryland
10:15 a.m.-12:15 p.m.
Role of human papillomaviruses in carcinogenesis
Massimo Tommasino, International Agency for Research on Cancer, Lyon, France
Prevention of hepatocellular carcinoma through preventative hepatitis C vaccination
Andrea Cox, Johns Hopkins University, Baltimore, Maryland
Interception of premalignant intraepithelial lesions: Lessons learned from HPV
Cornelia Liu Trimble, Johns Hopkins School of Medicine, Baltimore, Maryland
Novel phages targeting the intratumor-associated bacteria Fusobacterium nucleatum*
Lior Zelcbuch, BiomX, Ness Ziona, Israel
Lunch on Own
12:30-2:30 p.m.
Plenary Session 6: Microbiota and Gastrointestinal Cancers
Session Chair: Giorgio Trinchieri, National Cancer Institute, Baltimore, Maryland
2:30-4:30 p.m.
Title to be announced
Florencia McAllister, University of Texas MD Anderson Cancer Center, Houston, Texas
Fungal infection and carcinogenesis
Yinling Hu, National Cancer Institute, Bethesda, Maryland
Gut microbiota dysbiosis and dietary fermentable fibers in a pickle: A brew for liver cancer
Matam Vijay-Kumar, The University of Toledo, Toledo, Ohio
Deciphering the human gut microbiome with chemistry
Emily Balskus, Harvard University, Cambridge, Massachusetts
Keynote Address
4:30-5:30 p.m.
The role of the intestinal microbiome in allogeneic hematopoietic cell transplantation
Marcel R.M. van den Brink, Memorial Sloan Kettering Cancer Center, New York, New York
Poster Session B / Reception
5:45-7:45 p.m.
Monday, February 24
Continental Breakfast
7:30-8:30 a.m.
Plenary Session 7: Microbiota in Cancer Prevention and Therapy, Part 1
Session Chair: Cynthia L. Sears, Johns Hopkins University School of MEdicine, Baltimore, Maryland
8:30-10:30 a.m.
Non-canonical cross-presentation uncovers a tissue-resident CD8 T cell response
Julie Magarian Blander, Weill Cornell Medical College, New York, New York
Engineered Salmonella for drug delivery to solid tumors
Neil S. Forbes, University of Massachusetts Amherst, Amherst, Massachusetts
Gut microbiota control systemic T cell polarization and promote cancer
Andrea Facciabene, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
Novel microbiome-derived peptides modulate immune cell activity and the tumor microenvironment*
Dhwani Haria, Second Genome, South San Francisco, California
Postmenopause as a key factor in the composition of the Endometrial Cancer Microbiome (ECbiome): Putative role of Porphyromonas somerae in the disease*
Marina Walther-Antonio, Mayo Clinic, Rochester, Minnesota
Break
10:30-10:45 a.m.
Plenary Session 8: Microbiota in Cancer Prevention and Therapy, Part 2
Session Chair: Bertrand Routy, Centre Hospitalier de l’Universite de Montréal, Montreal, Quebec, Canada
10:45 a.m.-12:45 p.m.
The role of the tumor and gut microbiome in cancer
Jennifer A. Wargo, The University of Texas MD Anderson Cancer Center, Houston, Texas
Linking the gut microbiome to cancer treatment response
Bertrand Routy
Targeting the microbiome in cancer immunotherapy
Giorgio Trinchieri, National Cancer Institute, Bethesda, Maryland
Candida albicans infection mediates gastrointestinal track malignancy independently of Il17a in an APECED mouse model*
Feng Zhu, Laboratory of Cancer Immunometabolism, Center for Cancer Research, National Cancer Institute, NIH, Frederick, Maryland
Entero-mammary microbiota signaling axis regulates dietary influences on breast cancer risk*
Katherine Cook, Wake Forest University School of Medicine, Winston-Salem, North Carolina