The FDA approved the claudin 18.2-targeted therapy Zolbetuximab-clzb for some gastric and gastroesophageal junction cancers. The U.S. Food and Drug Administration (FDA) has approved zolbetuximab-clzb (Vyloy) plus a chemotherapy regimen consisting of fluoropyrimidine- and platinum-containing...
The PI3K inhibitor is approved as part of combination therapy for certain patients whose breast cancer recurred on or after endocrine therapy. The U.S. Food and Drug Administration (FDA) approved inavolisib (Itovebi), in combination...
The immunotherapy is now approved to treat certain lung cancers before and after surgery. The U.S. Food and Drug Administration (FDA) has approved neoadjuvant nivolumab (Opdivo) with platinum-containing chemotherapy, followed by adjuvant nivolumab alone,...
The accelerated approval of selpercatinib for certain patients with thyroid cancer was converted to a full approval. The U.S. Food and Drug Administration (FDA) has granted full approval to selpercatinib (Retevmo) for patients 2...
The EGFR inhibitor osimertinib is now available as a monotherapy for certain patients with locally advanced, unresectable non-small cell lung cancer. The U.S. Food and Drug Administration (FDA) has approved osimertinib (Tagrisso) to treat...
The CD38-targeted antibody was approved for patients who are ineligible for stem cell transplant. The U.S. Food and Drug Administration (FDA) has approved isatuximab-irfc (Sarclisa) in combination with VRd (a regimen consisting of bortezomib...
Amivantamab with carboplatin and pemetrexed was approved for some advanced non-small cell lung cancers that progressed on or after EGFR inhibition. The U.S. Food and Drug Administration (FDA) has approved amivantamab-vmjw (Rybrevant) plus the...
Some patients with stage 2 or 3 breast cancer may now receive ribociclib with an aromatase inhibitor after surgery. The U.S. Food and Drug Administration (FDA) has approved ribociclib (Kisqali) in combination with an...
Pembrolizumab plus chemotherapy was approved for certain patients with untreated malignant pleural mesothelioma. The U.S. Food and Drug Administration (FDA) has approved pembrolizumab (Keytruda) with the chemotherapeutic pemetrexed and platinum-based chemotherapy as first-line therapy...
The FDA approved atezolizumab and hyaluronidase-tqjs for all adult indications of intravenous atezolizumab. The U.S. Food and Drug Administration (FDA) has approved atezolizumab and hyaluronidase-tqjs (Tecentriq Hybreza) as a subcutaneous injection to be offered...
AACR Fellow Lewis C. Cantley, PhD, leads a national effort targeting triple-negative breast cancer and ovarian cancer with a novel drug combination.
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