Scientific Areas of Expertise: Chromosomal Translocations, Protein Engineering, Protein Macromolecule Delivery Mechanisms
For fundamental work involving the characterization of human antibody and T-cell receptor gene diversity and rearrangement, establishing cDNA cloning technology widely used in molecular biology, discovery of chromosomal translocation genes in cancer, and creating the first gene fusion knock-in mice, work that has led to the development of methods using intracellular antibodies for small molecule drug discovery applied to hard-to-drug targets including mutant RAS and LMO2.
*Full-length biography pending