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Research Funding Impact

Since 1993, the AACR has awarded more than $540 million in grants to fund meritorious research projects across the spectrum of cancer science, including basic, translational, and clinical research. See how the AACR grants program has contributed to the AACR's mission.

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Revolutionizing Uveal Melanoma Treatment: SCANDIUM-II Trial Combines Chemotherapy and Immunotherapy for Promising Results 

Revolutionizing Uveal Melanoma Treatment: SCANDIUM-II Trial Combines Chemotherapy and Immunotherapy for Promising Results 

Roger Olofsson Bagge, MD, PhD, recipient of the 2021 AACR-OMF Career Development Award, in honor of Robert C. Allen, MD, shares how the recent SCANDIUM-II clinical trial found that isolated hepatic perfusion with melphalan in combination with immunotherapies, ipilimumab and nivolumab was efficacious in the treatment of patients with liver-dominant metastases of uveal melanoma, but associated with severe adverse events.

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Illuminating metabolism: A pioneering approach to combat pancreatic cancer

Illuminating metabolism: A pioneering approach to combat pancreatic cancer

Costas Lyssiotis, PhD, received the 2013 Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant, 2016 AACR-Bayer Innovation and Discovery Award, and 2017 AACR NextGen Grant for Transformative Cancer Research. Dr. Lyssiotis shares how these three AACR grants helped him and his team discover several mechanisms by which metabolites support tumor growth, immune evasion, and resistance to therapy in pancreatic cancer.

Category: Grantee Story
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Lymphatic Vessels: Enabling Defense on Two Fronts

Lymphatic Vessels: Enabling Defense on Two Fronts

In a war, first-line troops are essential -- such are resident memory T cells (TRM), standing guard at peripheral sites, ready to fight infections and cancer. The Laboratory for Lymphatic Immunobiology, led by 2022 AACR-Bristol Myers Squibb Midcareer Female Investigator Grant Recipient Amanda Lund, PhD, seeks to understand how transport of TRMs through lymphatic vessels helps facilitate critical peripheral immune responses to antigen, whether presented by infectious agents or cancer cells.

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TTFields: A Potential Treatment of Spinal Metastases

TTFields: A Potential Treatment of Spinal Metastases

Claudio E. Tatsui, MD, recipient of the 2021 AACR-Novocure Tumor Treating Fields Research Grant, and Christopher A. Alvarez-Breckenridge, MD, PhD, recipient of the 2023 AACR-Novocure Career Development Award for Cancer Research recently uncovered how the emerging treatment modality Tumor Treating Fields (TTFields) could be leveraged as a local therapy in the treatment of spinal metastases.

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AACR Grantees Take the Stage at the AACR Annual Meeting 2024

AACR Grantees Take the Stage at the AACR Annual Meeting 2024

The AACR Annual Meeting 2024 took place April 5–10 in San Diego, California, with over 23,200 registrants, including more than 22,000 in-person attendees from 78 countries and territories participating in the meeting. A number of past and present AACR grantees were invited to present their work as poster or oral presentations at the meeting.

Category: Grantee News
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Neutrophils Pave the Way for Chronic Stress-Induced Cancer Metastasis

Neutrophils Pave the Way for Chronic Stress-Induced Cancer Metastasis

Xue-Yan He, PhD, was awarded the AACR-AstraZeneca Breast Cancer Research Fellowship in 2021. During her postdoctoral fellowship, Dr. He uncovered how neutrophils create a pro-metastatic environment in response to chronic stress. The results of this study highlight the potential of stress reduction as a strategy for cancer patients to improve treatment outcome.

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2024 AACR Annual Meeting Meet the Research Grant Reviewers Event Offers a Unique Opportunity to Interact with AACR Research Grant Reviewers 

2024 AACR Annual Meeting Meet the Research Grant Reviewers Event Offers a Unique Opportunity to Interact with AACR Research Grant Reviewers 

On Monday, April 8, 2024, attendees of the 2024 AACR Annual Meeting are invited to participate in a unique opportunity to interact with two of our research grant reviewers! This year we are thrilled to have reviewers Sandeep Burma, PhD, FNASc and Christine M. Lovly, MD, PhD answer your questions during this session. We offer you an introduction to our speakers and share what attendees can hope to gain from this event. 

Category: Grantee News
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