
Michele Carbone: Gene hunter of Hawai’i
Michele Carbone, MD, PhD, investigated an epidemic of mesothelioma in remote villages in Turkey and discovered a new cancer syndrome caused by an inherited anomaly. An AACR grant supported his research.
Since 1993, the AACR has awarded more than $540 million in grants to fund meritorious research projects across the spectrum of cancer science, including basic, translational, and clinical research. See how the AACR grants program has contributed to the AACR's mission.
Michele Carbone, MD, PhD, investigated an epidemic of mesothelioma in remote villages in Turkey and discovered a new cancer syndrome caused by an inherited anomaly. An AACR grant supported his research.
The AACR-Conquer Cancer Foundation (CCF) of ASCO Young Investigator Award for Translational Cancer Research funds a physician-scientist during the transition from a fellowship program to a faculty appointment. 2020 Recipient Dr. Mathios speaks on the grant's impact on his research and career.
The 2020 AACR-The Mark Foundation for Cancer Research “Science of the Patient” SOP Grants Program seeks to stimulate novel research on the interplay between patient physiology and the tumor. The five grantees have been conducting breakthrough research -- studying cancer not as an isolated phenomenon but as a systemic disease.
Sarah Bohndiek, PhD, of the University of Cambridge. once thought she wanted to be an astrophysicist. She trained instead in radiation physics, and a grant from the AACR and Amgen helped her move into molecular imaging and early detection of cancer.
A grant from the AACR in 2000 helped Karlyne Reilly, PhD, launch her career in cancer research. She is now head of the Rare Tumor Initiative at the National Cancer Institute and works to involve scientists, patients, family members, advocates, and healthcare providers in the search for treatments for rare cancers.
Cachexia is a muscle-wasting syndrome that is commonly found in pancreatic and other cancer patients. A group led by 2017 Pancreatic Cancer Action Network-AACR Career Development Award recipient Jason D. Doles, PhD, identified Perp as a novel tumor promoter and mediator of cancer-associated muscle wasting.
The AACR-AstraZeneca Clinical Immuno-oncology Research Training Fellowship Program is designed to encourage exceptional clinical research by bridging close collaboration between academia and industry. 2020 grant recipient Justin A. Chen, shares his perspectives on the impact of the grant.
2019 AACR-Amgen Fellow, Julia Frede, PhD, reported in Nature Cell Biology, how treatment can induce the expression of a distinct set of actionable immunotherapy targets in multiple myeloma, such as CXCR4, which can be exploited to keep treatment resistance at bay.
For David A. Tuveson, MD, PhD, FAACR, a career development grant from the AACR initiated the development of a model to help understand one of the deadliest and most difficult-to-treat types of cancer.
At the start of his career, Sunil Hingorani, MD, PhD, now at the Fred Hutchinson Cancer Research Center, had a life-altering experience in caring for a patient with pancreatic cancer. A grant from the AACR in 2005 led him into an investigation that changed his approach to the disease.