Since 1993, the AACR has awarded more than $540 million in grants to fund meritorious research projects across the spectrum of cancer science, including basic, translational, and clinical research. See how the AACR grants program has contributed to the AACR's mission.
The AACR-Bayer START grant gives early career investigators the unique opportunity to gain experience not only in academic but also in industry settings. Mark Labrecque, PhD, speaks on the impact of this grant on his career and research.
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been primarily studied in the context of autoimmune diseases. 2019 AACR-InCyte Immuno-oncology Fellow Won Jin Ho, MD, showed how PTPN22 inhibition retards tumor growth in a T-cell- and macrophage-dependent manner.
In recognition of the need to advance the science of lung cancer prevention and interception, the 2019 AACR-J&J Lung Cancer Innovation Science Grants program awarded grants to two multi-institutional teams whose multifaceted projects seek to understand how an individual’s genetics may affect smoking-related behaviors and quit attempts, as well as to develop clinically actionable smoking cessation strategies that will improve patient outcomes.
More than half of melanomas contain extra copies of the sirtuin 5 gene. Two AACR-Bayer Innovation and Discovery grant recipients and an AACR NextGen Grant recipient, along with their colleagues, demonstrated that sirtuin 5 is required for melanoma cell proliferation and survival.
AACR grantee Yi Fan, PhD, shared how flexible funding from an AACR Judah Folkman Career Development Award allowed him to explore an unconventional angle of anti-vascular therapy; namely, targeting genetic endothelial transformation, to fight the deadliest of brain cancers.
When Matthew Vander Heiden was working on his MD/PhD, trying to understand how apoptotic cell death is regulated by bcl-2 proteins located at the mitochondrial outer membrane, it occurred to him he would have to go back to basics.
The partnership of the AACR with QuadW reflects the commitment of both organizations to make a difference in the lives of sarcoma patients by supporting the next generation of cancer researchers who are focused on sarcoma research.
It has long been suggested that consumption of red meat increases the risk of colon cancer. Scientists have now demonstrated a possible mechanistic link between the two in human tumors
The AACR-Bristol Myers Squibb Midcareer Female Investigator Grant is the AACR’s first dedicated funding mechanism for midcareer scientists, as well as the first dedicated for women. The goal is to ensure that midcareer female researchers have the resources they need to successfully establish themselves as independent investigators with productive research labs.
A team of investigators led by 2015 KureIt-AACR Grantee Dr. Eliezer Van Allen and Dr. Toni Choueiri probed the changes in the tumor and immune system in advanced renal cell carcinoma patients who received immune check point blockade (ICB).